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in the nucleus of a cell, the three-dimensional conformation of the genome has a major impact on how it functions. A better understanding of the links between the 3D structure of the genome and its functioning represents a methodological challenge and requires dialogue between different disciplines

Understanding the genetic determinism of a trait, i.e. the set of genes involved in the development and expression of this trait, is a major challenge for better understanding biological processes and supporting genetic improvement programmes.

In biology, as in other scientific fields, the integration of multi-source data is more relevant than ever. Indeed, the data collected are increasingly complex and their volume is growing, due to the development of analytical platforms, imaging techniques, the rise of omics data, etc

In response to the multiple challenges of climate change and multi-performance agriculture, the sciences of breeding and plants are faced with the challenge of selecting breeds or varieties on the basis of increasingly complex phenotypes.

The IFM2A2 consortium proposes to bring together in a sustainable manner the different scientific communities that are currently working separately on simulating the functioning of apical meristems at different scales, operating in different INRAE departments (BAP, MAthNum and AgroEoSystem) in close interaction with INRIA.

A major issue in in vitro fertilisation (IVF) is the selection of the "best" embryo, i.e. the one most likely to implant in the uterus. The objective of the BovMovie2Pred consortium is to propose solutions to assist in the selection of bovine embryos in order to increase the percentage of viable births from in vitro produced embryos.